Z. Xiang, T. P. Luo, K. Lu, J. Y. Cui, X. Shi, R. Fathi, J. H. Chen*, Z. Yang*

Org Lett. 2004, 6, 3155.

Two types of isoquinoline scaffolds were successfully constructed in a combinatorial format via the Ugi four-component reaction and the Pd-catalyzed intramolecular Heck reaction, starting from readily available starting materials.